Novel, Simple, Sensitive and Rapid Spectrophotometric Methods for the Determination of Cardol using Sulfanilamides as New Class of Coupling Reagents

Publication Date : 26/10/2015


Author(s) :

Akheel Ahmed Syed , Mohsina Begum , Isa Baba Koki .


Volume/Issue :
Volume 1
,
Issue 10
(10 - 2015)



Abstract :

First-ever three spectrophotometric methods using sulfanilamide (SAA), sulfadoxine (SDX) and sulfamethoxazole (SMX), the widely used sulfa drugs as new class of coupling agents for the spectrophotometric determination of cardol, a phenolic compound found in cashew nut shell liquid, a by-product of cashew industry is proposed. The methods are based on the interaction of diazotized sulfa drugs with cardol to produce an orange yellow colored product with a maximum absorption at 440 nm. The color developed was stable up to 6 h. The methods obey Beer’s law. The methods can be successfully employed for the determination of cardol in presence of anions and cations, which do not interfere in the methods. Key words: Cardol, Diazotization, Sulfanilamide, Sulfadoxine, Sulfamethoxazole, Spectrophotometry


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