The antifungal activity of aqueous and methanolic extracts of ten different Indian medicinal plants were assessed using agar well diffusion test against four different fungi viz, Candida albicans, Aspergillus fumigatus, Aspergillus parasiticus and Cryptococcus sp.The assessment of the minimum inhibitory concentrations of the active extracts were carried out using serial dilution plate technique. A. fumigatus was found to be sensitive to eight out of the ten alcoholic extracts tested where as Cryptococus alone was found sensitive to the aqueous extracts. The alcoholic extract of the seed coat of Tamarindus indica and leaf of Allophyllus cobbe inhibited the growth of C. albicans and A. fumigatus at 12.5 mg/ml where as leaf extracts of Azadirachta indica, Annona squamosa, Mallotus phillipensis and Chromoleana odorata at the same dose rate inhibited the growth of A. fumigatus alone. From the study it could be concluded that eight out of the ten alcoholic extracts tested form promising leads for synthesis of novel antifungal agents.
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