Self Emulsifying Drug Delivery System for Improving Bioavailability

Publication Date : 22/12/2016


Author(s) :

Akanksha Agrawal , Arti J. Majumdar , Ankur jain.


Volume/Issue :
Volume 2
,
Issue 12
(12 - 2016)



Abstract :

Oral route is the most common and convenient route for drug delivery, but some drugs are not given by this route. This route is most common problem is low bioavailability .The various challenges faced by the pharmaceutical scientists leads to the improve bioavailibilityty enhance the approach of self emulsifying drug delivery system. It has gained exposure of their ability to increase solubility and improve the bioavailability of poorly soluble drugs. SEEDS being a lipid based formulations consist oils ,surfactants, solid lipid nanoparticles ,dispersion, emulsion and liposomes .Different type SEEDDS are available in market like as oral drud delivery, Topical delivery, parental drug delivery, ocular & pulmonary drug delivery .Different type of oral dosage forms ae availaalbe in the market like as Self emulsifying capsule,Self emulsifying controlled release pellets, Self emulsifying sustained/controlled release pellets, Self emulsifying solid dispersion. In drug detection and growth solubility has an important role in various step to import high bioavalibilty and to gain required pharmalogical action due o low aqueous solubility,effect the lipophilic drug. Lipophilic drug has shown low bribability when aqueous solubility has low.


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