Studies the effect of ionic strength of medium on the thermodynamic parameters of etodolac with Cu (II), Zn (II) complexes

Publication Date : 25/04/2016


Author(s) :

A.N. SONAR.


Volume/Issue :
Volume 2
,
Issue 4
(04 - 2016)



Abstract :

The metal-ligand and proton–ligand stability constant of Cu(II) and Zn(II) with substituted heterocyclic drug (Etodolac) were determined at various ionic strength by pH metric titration. NaClO4 was used to maintain ionic strength of solution. The results obtained were, extrapolated to the zero ionic strength using an equation with one individual parameter. The thermodynamic stability constant of the complexes were also calculated.


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