CHARACTERISATION AND COMPARISON OF HUMAN DENTAL PULP STEM CELLS OBTAINED FROM DIFFERENT TYPES OF TOOTH
Publication Date : 16/04/2018
Mesenchymal stem cells (MSCs) have been receiving a lot of attention in various pre-clinical and clinical studies owing to their multipotency property and self renewal ability. Although mesenchymal stem cells exist in many tissues, human tooth is regarded as one of the rich source of mesenchymal stem cells with distinct advantages over other sources. Ability to retain their stem cell properties post cryopreservation, ease of collection, wider window with multiple tooth options for accessing the stem cells have aroused interest in banking dental pulp stem cells for potential future. This has led to emergence of dental stem cell banks similar to umbilical cord blood across the world. All teeth are known to harbour stem cells in the pulp tissue and can be considered for stem cell banking. However, if one has to make a choice of any one tooth to be collected for banking there is no comparative analysis of the stem cells isolated from various tooth types like the incisors, canines, premolars or molars. This study focuses on the identification, characterisation and comparison of human dental pulp stem cells from different tooth types to evaluate if there are any distinctive differences between them and if any one tooth type has a significant edge over other as dental stem cell banking candidates.
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